Annalisa Marcuzzi Selected Research

Terpenes (Terpenoids)

4/2014	Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds.
9/2013	Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients.
10/2012	Lovastatin-induced apoptosis is modulated by geranylgeraniol in a neuroblastoma cell line.
1/2011	Geraniol rescues inflammation in cellular and animal models of mevalonate kinase deficiency.
6/2010	Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.
5/2010	Decreased cholesterol levels reflect a consumption of anti-inflammatory isoprenoids associated with an impaired control of inflammation in a mouse model of mevalonate kinase deficiency.
8/2008	Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Annalisa Marcuzzi Research Topics

Disease

19	Mevalonate Kinase Deficiency 01/2021 - 08/2008
15	Inflammation (Inflammations) 04/2021 - 08/2008
6	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2019 - 12/2014
5	Rare Diseases (Rare Disease) 05/2018 - 06/2010
4	Neoplasms (Cancer) 03/2022 - 10/2012
3	Infections 01/2019 - 10/2012
3	Mitochondrial Diseases (Mitochondrial Disease) 05/2018 - 04/2014
3	Crohn Disease (Crohn's Disease) 11/2016 - 01/2013
2	Virus Diseases (Viral Diseases) 03/2022 - 01/2013
2	Ulcerative Colitis 11/2016 - 12/2014
1	Primary Myelofibrosis (Myelosclerosis) 03/2022
1	Cytokine Release Syndrome 03/2022
1	Polycythemia (Erythrocytosis) 03/2022
1	Graft vs Host Disease (Graft-Versus-Host Disease) 03/2022
1	Hyperamylasemia 08/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 08/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2021
1	Atherosclerotic Plaque (Atheroma) 01/2021
1	Vitamin D Deficiency 01/2021
1	Lymphopenia (Lymphocytopenia) 01/2020
1	Encephalitis (Encephalitis, Rasmussen) 01/2020
1	Eosinophilia 01/2020
1	Exanthema (Rash) 01/2020
1	Melanoma (Melanoma, Malignant) 01/2020
1	Mucositis 01/2020
1	Immune Reconstitution Inflammatory Syndrome 01/2020
1	Drug Hypersensitivity Syndrome 01/2020
1	Drug-Related Side Effects and Adverse Reactions 01/2020
1	Proteinuria 12/2019
1	Nephrotic Syndrome (Syndrome, Nephrotic) 12/2019
1	Smith-Lemli-Opitz Syndrome 04/2019
1	Metabolic Diseases (Metabolic Disease) 12/2018
1	Obesity 12/2018
1	Vulvodynia 07/2018
1	Neonatal Anemia 12/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 12/2017
1	Joint Diseases (Joint Disease) 12/2017
1	Hematologic Diseases (Blood Diseases) 12/2017
1	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 12/2017
1	Bone Fractures (Bone Fracture) 09/2015

Drug/Important Bio-Agent (IBA)

10	Mevalonic Acid (Mevalonate)IBA 04/2016 - 06/2010
9	CholesterolIBA 01/2021 - 05/2010
9	CytokinesIBA 12/2019 - 07/2011
7	Terpenes (Terpenoids)IBA 04/2014 - 08/2008
4	InflammasomesIBA 03/2016 - 01/2012
3	Pharmaceutical PreparationsIBA 01/2020 - 01/2013
3	EnzymesIBA 04/2019 - 01/2013
3	Proteins (Proteins, Gene)FDA Link 09/2015 - 01/2012
3	Alendronate (Alendronate Sodium)FDA LinkGeneric 09/2015 - 08/2008
3	ChemokinesIBA 06/2015 - 10/2012
3	geranylgeraniolIBA 10/2012 - 08/2008
3	geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA 07/2011 - 06/2010
2	InterleukinsIBA 01/2020 - 12/2018
2	CurcuminIBA 06/2017 - 12/2014
2	Lovastatin (Mevacor)FDA LinkGeneric 12/2013 - 10/2012
2	mevalonate kinaseIBA 09/2013 - 01/2013
2	LipopolysaccharidesIBA 10/2012 - 09/2011
2	geraniol (nerol)IBA 03/2012 - 01/2011
2	Pamidronate (Aredia)FDA LinkGeneric 06/2011 - 01/2011
1	ruxolitinibIBA 03/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2021
1	mitoquinoneIBA 04/2021
1	Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)IBA 01/2021
1	Phosphorus (Red Phosphorus)IBA 01/2021
1	paricalcitol (Zemplar)FDA Link 01/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	CalciumIBA 01/2021
1	1- ((1- (3- acetoxy- 2,2- dimethylpropyl)- 7- chloro- 5- (2,3- dimethoxyphenyl)- 2- oxo- 1,2,3,5- tetrahydro- 4,1- benzoxazepin- 3- yl)acetyl)piperidine- 4- acetic acidIBA 01/2021
1	Vitamin D FDA LinkGeneric 01/2021
1	Triglycerides (Triacylglycerol)IBA 01/2021
1	tocilizumab (atlizumab)FDA Link 01/2020
1	trametinibIBA 01/2020
1	dabrafenibIBA 01/2020
1	Infliximab (Remicade)FDA Link 01/2020
1	VemurafenibIBA 01/2020
1	NivolumabIBA 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	AntigensIBA 01/2020
1	GlobulinsIBA 01/2020
1	SteroidsIBA 12/2019
1	Long Noncoding RNAIBA 10/2019
1	Matrix Metalloproteinases (MMPs)IBA 10/2019
1	growth arrest specific transcript 5IBA 10/2019
1	Immunoglobulin M (IgM)IBA 01/2019
1	VaccinesIBA 01/2019
1	LipidsIBA 12/2018
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2018
1	Interleukin-1 (Interleukin 1)IBA 01/2018
1	InterferonsIBA 12/2017
1	Antinuclear AntibodiesIBA 12/2017
1	Volatile Organic CompoundsIBA 01/2017
1	Acetylmuramyl-Alanyl-IsoglutamineIBA 11/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 03/2016

Therapy/Procedure

4	Therapeutics 01/2020 - 07/2011
2	Hematopoietic Stem Cell Transplantation 03/2022 - 08/2021
1	Immunotherapy 03/2022
1	Cell- and Tissue-Based Therapy (Cell Therapy) 03/2022
1	Injections 01/2021
1	Biological Therapy 01/2018